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| CellufineTM is the trademark of JNC Corporation, Tokyo, Japan |
2020/11/16: Product under development: Introduction of r-Trypsin immobilized resin for insulin production
2020/11/9： Change notirication: Add manufacturing site of Cellufine C-500（PDF）
2020/10/16： Notification Letter concerning addition of raw material supplier（PDF）
2020/4/13： Change notification of certification of analysis sheet（PDF）
2020/3/23： Change notification of Cellufine Q-500（PDF）
2019/9/13： Product Discontinuation Notice of Cellufine Amino and Cellufine Chelate.（PDF）
2019/2/8： Change notification of raw material of “CellufineTM Sulfate".（PDF）
2018/11/20： Introduction of new high capacity rProtein A resin “CellufineTM SPA-HC"（PDF）
2018/8/21： New product! AFF media CellufineTM MAX DexS-VirS（PDF）
New product! AFF media CellufineTM MAX DexS-HbP（PDF）
2018/8/20： See you in BPI-East 2018 Conference (Booth # 1819)（PDF）
2018/3/22： Detailed Information of the Product Change Notification (Cellufine mini column)（PDF）
2017/2/27： New Product; Introduction of mixed mode resin Celluhine MAX IB（PDF）
| The Cellufine product line consists of chromatography media designed for the purification of proteins, enzymes, and other biomolecules. This media line is based on spherical cellulose beads, which exhibit high chemical stability, high mechanical strength, and inherent bio-compatibility. These Cellufine chromatography products are ideally suited for the purification of biopharmaceuticals and food products. And leachables from cellulose based media are significantly lower than for comparable polymeric beads. Cellufine chromatography products are appropriate for all chromatographic techniques. Gel Filtration, Ion Exchange, Affinity, and Hydrophobic Interaction chromatography media are available for peroration of a broad range of target molecules. In addition, JNC Corp. can provide custom media, such as big beads or special affinity ligands, for use in challenging purification process. |
Cellufine chromatography media is |
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Typical applications include protein and polysaccharide purification, and endotoxin removal. Cellufine media is used worldwide in chromatographic purification of vaccines, therapeutic enzymes and proteins, and virus concentration/purification. |
Cellufine chromatography media is |
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JNC pioneered cellulose bead formation technology which provides Cellufine products robust, spherical, porous beads. Cellulose based chromatography media can be efficiently packed in deep beds in chromatography columns and are capable of operating at high velocities. Cellufine beads are optimized for each chromatographic technique to provide the high efficiencies demanded in biopharmaceutical manufacturing. |
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Modification of basic cellulose matrix with different ligands assures an efficient and economical purification of broad range of bio-molecules. |
The Product Range of Cellufine Chromatograpy Media |
| Cellufine media products are appropriate for all modes of chromatography: Ion Exchange, Affinity, Hydrophobic Interaction, Mix mode and Gel Filtration. The table below lists available standard products. In addition, customized products can be developed by modifying bead size, porosity, and ligand chemistry. Cellufine products are packaged in a variety of container sizes ranging from 10 ml to 10 L. In addition to standard bottles, most products are available in mini-column formats with media volumes of 1ml. Larger packaging containers are available on request. |
| CHROMATOGRAPHY MEDIA PRODUCT RANGE |
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Under Developing product: r-Trypsin immobilized resin |
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This is an enzyme immobilized resin which recombinant trypsin used for insulin production is immobilized on cellulose particles.
Since trypsin is covalently bound to cellulose particles, trypsin activity is much more stable than free trypsin.
From this feature, it can be expected to reduce the manufacturing cost by repeated use of trypsin digestion.
Click here for details! Introduction page of r-Trypsin immobilized resin |
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